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The Code Breaker by Walter Isaacson

Nonfiction

The Code Breaker

by Walter Isaacson

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Volume 0
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Quick take

A fascinating account of how a female scientist and her team invented a groundbreaking technology: a tool to edit DNA.

Good to know

  • Illustrated icon, 400

    400+ pages

  • Illustrated icon, Brainy

    Brainy

  • Illustrated icon, Buzzy

    Buzzy

  • Illustrated icon, Techie

    Tech world

Synopsis

When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.

Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ?a curiosity ?of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions.

The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code.

Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm… Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids?

After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is a thrilling detective tale that involves the most profound wonders of nature, from the origins of life to the future of our species.

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Nonfiction
View all
Dead Wake
Killers of the Flower Moon
The Girl Who Smiled Beads
Thick
The Sky Is Falling
Small Fry
Too Much Is Not Enough
All That You Leave Behind
Doing Justice
Falter
The Players Ball
Bitcoin Billionaires
Leaving the Witness
City of Omens
Eyes in the Sky
On The Clock
Wild Game
My Friend Anna
Trick Mirror
Tightrope
Evicted
Big Friendship